Healthcare Resource
Healthcare Recruiting in South Carolina 2026: Top Employers, Pay, and Demand
In brief
Guide to healthcare recruiting in South Carolina: Charleston, Columbia, Greenville, Myrtle Beach. Top employers (MUSC, Prisma, Roper), salary data.
In this article
South Carolina's healthcare market has been a net beneficiary of population migration from the Northeast and Midwest. Prisma Health (the largest nonprofit system in the state) and MUSC Health anchor major markets, with HCA and Roper St. Francis filling in coastal SC.
Top Healthcare Employers in South Carolina (2026)
| System | HQ | Employees | Hiring Focus 2026 |
|---|---|---|---|
| Prisma Health | Greenville | 32,000+ | Primary care, cardiology, oncology, nursing |
| MUSC Health | Charleston | 17,000+ | Academic subspecialties, research, transplant |
| Roper St. Francis Healthcare | Charleston | 7,500+ | Primary care, cardiology, women's health |
| HCA South Carolina | multiple | 5,500+ | Emergency medicine, hospitalists, surgery |
| AnMed Health | Anderson | 3,500+ | Primary care, cardiology, emergency medicine |
| Self Regional Healthcare | Greenwood | 2,500+ | Rural primary care, emergency medicine |
| Lexington Medical Center | West Columbia | 4,000+ | Primary care, cardiology, OB/GYN |
| McLeod Health | Florence | 4,500+ | Primary care, emergency medicine, cardiology |
| Grand Strand Medical Center (HCA) | Myrtle Beach | 1,500+ | Primary care, emergency medicine |
| Beaufort Memorial Hospital | Beaufort | 1,500+ | Primary care, emergency medicine |
South Carolina Salary Benchmarks (2026)
| Role | Median Base | Typical Sign-On |
|---|---|---|
| Nurse Practitioner | $112,000 | $10,000-$22,000 |
| RN (ICU) | $82,000 | $18,000-$35,000 |
| CRNA | $205,000 | $25,000-$50,000 |
Where the Demand Is Highest
Charleston: MUSC + Roper St. Francis compete for academic and community roles.
Columbia / Midlands: Prisma Health Midlands + Lexington Medical. Strong primary care demand.
Greenville / Upstate: Prisma Health Upstate anchors. AnMed in Anderson competes.
Florence / Pee Dee: McLeod Health. Rural shortage + loan repayment available.
Myrtle Beach / Grand Strand: Grand Strand Medical (HCA) + Tidelands Health. Retiree-driven primary care + cardiology demand.
Licensing Notes
- NP practice: SC requires collaborating physician (reduced practice)
- eNLC member, RNs with multistate license practice immediately
Use Ava Health's public market tools to research South Carolina's nursing and allied health workforce.
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